In May 2001, Cibrian married Brandi Glanville, a former model and reality television star. Cibrian and Glanville have two sons, Mason and Jake. The couple announced their separation in July 2009 after it was revealed Cibrian had an affair with country music singer LeAnn Rimes. Cibrian and Rimes appeared together in the 2009 movie Northern Lights. Cibrian and Glanville’s divorce was finalized on September 30, 2010. The circumstances surrounding the affair and divorce were a part of Glanville’s book Drinking and Tweeting: And Other Brandi Blunders.

In 2006, Cibrian joined the cast of the Fox series Vanished midway through the season. The series was canceled after nine of the thirteen episodes produced were aired with subsequent episodes released via Myspace. The following year, he was cast as Jason Austin in the unaired pilot of Football Wives, the ABC remake of the British drama Footballers Wives.

Cibrian has had guest spots on Samantha Who?, Dirty Sexy Money, and Ugly Betty. In 2009, he joined the cast of CSI: Miami as an officer from the Hollywood division who joins Horatio’s team in Miami. His contract was not picked up for the 2010–11 season.

In July 2010, Cibrian guest starred as a bounty hunter in multiple episodes of NBC’s drama series Chase.

On December 27, 2010, it was announced that Cibrian was engaged to Rimes. The couple wed on April 22, 2011, at a private home in California.

In March 2011, Cibrian was cast as the lead in the NBC pilot for The Playboy Club, a TV series set at the first Playboy Club in Chicago in 1963. In early October 2011, The Playboy Club was canceled by NBC after three episodes due to low ratings. In 2016, he was added to the cast of Rosewood as Capt. Ryan Slade. In 2018, he starred as the Private Investigator, Eddie Valetik, in Take Two on ABC.