Purviance was born in Paradise Valley, Nevada to English immigrant Louisa Wright Davey and American vintner to the western mining camps Madison (Matt) Gates Purviance. When she was three, the family moved to Lovelock, Nevada, where they assumed ownership of a hotel. Her parents divorced in 1902, and her mother later married Robert Nurnberger, a German plumber. Growing up, Purviance was a talented pianist.

She left Lovelock in 1913, and moved in with her married sister Bessie while attending business college in San Francisco.

In 1915, Purviance was working as a secretary in San Francisco when actor and director Charlie Chaplin was working on his second film with Essanay Studios, working out of Niles, California, 28 miles southeast of San Francisco, in Southern Alameda County. He was looking for a leading lady for A Night Out. One of his associates noticed Purviance at a Tate’s Café in San Francisco and thought she should be cast in the role. Chaplin arranged a meeting with her, but he was concerned that she might be too serious for comedic roles. Purviance still won the role.

Chaplin and Purviance were romantically involved during the making of his Essanay, Mutual, and First National films of 1915 to 1917. Purviance appeared in 33 of Chaplin’s productions, including the 1921 The Kid. Her last credited appearance in a Chaplin film, A Woman of Paris, was also her first leading role. The film was not a success and effectively ended Purviance’s career. She appeared in two more films: Sea Gulls, also known as A Woman of the Sea (which Chaplin never released) and Éducation de Prince, a French film released in 1927.

Romantically involved with Charlie Chaplin for several years, Purviance eventually married John Squire, a Pan-American Airlines pilot, in 1938. They remained married until his death in 1945.

On January 13, 1958, Purviance died from throat cancer at the Motion Picture Country Hospital in Woodland Hills, California. Her remains are interred at Grand View Memorial Park Cemetery in Glendale, California.