Tynes re-signed for the Chiefs and was ready to be the next full-time kicker for the team. During the 2004 season, he converted 17 field goals out of 23 opportunities. In 2005, he made 27 field goals out of 33 opportunities. In 2006, he made 24 field goals out of 31 opportunities.

On August 17, 2005, Tynes turned himself into Pierce County, Wisconsin jail after punching a bar patron and breaking a bouncer’s nose in a bar fight the previous weekend (the Chiefs’ training camp at the time was based out of River Falls). Tynes was charged with one felony count of substantial battery and one count of misdemeanor battery. He was released on a $15,000 signature bond. Tynes paid a $397 fine for the incident.

Tynes’s first year with the Giants was successful as he converted 27 field goals out of 32 opportunities in the 2007 season. During the NFC Championship game in Green Bay against the Packers, played in sub-zero temperatures, Tynes hit his first two field goal attempts, then missed two field goal attempts in the fourth quarter, the latter after a bad snap. In overtime he made the game-winning 47 yard field goal to win the game for the Giants, 23-20, as the team moved on to play in the Super Bowl with the win. Tynes earned his first career championship ring as the Giants defeated the New England Patriots in Super Bowl XLII, ruining what would have been an unprecedented 19-0 season for the Patriots.

During the 2009 season, Tynes converted 27 field goals out of 32 opportunities.

In 2011, Tynes converted 19 field goals out of 24 opportunities. During the NFC Championship game against the San Francisco 49ers, Tynes kicked another walk-off field goal in overtime to win the game, 20–17. Tynes got his second championship title as the Giants won Super Bowl XLVI against the Patriots. In the game, he converted one extra point and two field goals (a 38-yarder and a 33-yarder, both in the third quarter).

In the 2012 season, Tynes made a career-high 33 field goals out of 39 opportunities.

On July 17, 2013, the Buccaneers signed Tynes to a one-year contract worth $905,000 after Connor Barth suffered a season-ending torn Achilles tendon. He contracted the bacterial infection MRSA in August 2013, after surgery to remove an ingrown toenail failed to heal. After spending the entire season on injured reserve, Tynes was released on March 11, 2014,, and the infection effectively ended his NFL career. Tynes sued the Buccaneers in 2015 for $20 million, claiming that unsanitary conditions led to his MRSA infection. Other teammates, including Carl Nicks and Johnthan Banks, also contracted MRSA around the same time while with the Buccaneers, and while Nicks also found his career at an end, Banks went on to play several more seasons in the NFL. Tynes and the Buccaneers settled in 2017, the terms remaining confidential.