Lili Estefan was born on March 20, 1967 in Santiago de Cuba. Lili’s father is José Estefan (b. 1945). Upon losing her mother at the age of ten, Lili emigrated to the United States with her widower father and younger brother Juan Emilio (b. 1967). She is the paternal niece of music producer Emilio Estefan, whose wife is singer Gloria Estefan.

Estefan first came to the spotlight in 1986, when she was hired by Univision to participate as a model on the television show Sábado Gigante. She quickly became a favorite of the audience and the show host, Don Francisco, himself (as he admitted in his 2002 autobiography). Estefan even appeared on Francisco’s program “Don Francisco Presenta” on numerous occasions.

Estefan married Cuban businessman Lorenzo Lauces in 1992 and it was announced in 2018 that they were divorcing. They have two children: Lorenzo Jr. (b. 1999) and Lina Teresa (b. 2002).

In 2015, Lili Estefan received the Lifetime Achievement Award at the 33rd Annual Premios TVyNovelas, presented by Televisa. In 2016, Estefan and her co-host of El Gordo y La Flaca, Raúl de Molina, were honored with the award for Outstanding Achievement in Hispanic Television, at the 14th Annual Hispanic Television Summit, presented by Broadcasting & Cable and Multichannel News, and produced by Schramm Marketing Group. In 2017, Estefan received the Career Award at the Premio Lo Nuestro Awards, presented by Univision. In 2018, she received a Daytime Talent in Spanish Emmy Award from The National Academy of Television Arts & Sciences.