Paxton-Beesley graduated in 2008 from the George Brown Theatre School in Toronto, then went on to graduate from the Actors’ Conservatory at the Canadian Film Centre. Paxton-Beesley has been involved in stage work at The Company Theatre in Festen in 2008, at the Canadian Stage Company and the Citadel Theatre on Rock ‘n’ Roll in 2009, and at the Theatre Aquarius in The Woman in White. She returned to the stage in 2017 in Slip, a complex psychological drama in which she played a detective, at the Tarragon Theatre, her performance receiving high praise from Theatre Critic Karen Fricker.

Paxton-Beesley has performed acting roles in several different TV series, including Copper in 2012, an American Civil War drama, wherein she played Ellen Corcoran for 11 episodes, The Strain by Guillermo del Toro in 2014, Good Witch as Eve in 2015, and Wynonna Earp as Hetty Tate, 2016. She played the role of “Red”, a brain-damaged shooting victim, in six episodes of the TV series Cardinal in 2018 and in the same year starring as Anna Funk in Pure.