Chase was born in Chicago, Illinois. He spent time growing up between Barrington, Illinois and Naples, Florida, and went to high school in Jacksonville. He attended Duke University on a full football athletic scholarship, playing linebacker. He graduated in 1995 with a degree in psychology. Taking up acting as a career, he trained at the London Academy of Music and Dramatic Art, then moved to Los Angeles to work with the improv group, The Groundlings.

In 2012, he was cast as Deputy Branch Connally, a foil to the lead, on the A&E western mystery series Longmire.

Following his departure from Longmire, he appeared in 2016 on the NBC fantasy-drama Grimm as Lucien Petrovich, leader of the Wesen uprising. Chase appears in the fifth-season episodes “Eve of Destruction”, “Key Move,” and “Into The Schwarzwald”.

In September 2016, Deadline Hollywood announced that Chase had joined the cast of the Fox TV series 24: Legacy as Thomas Locke, agent and head of field operations at CTU. The show aired on February 5, 2017 following the Super Bowl, prior to moving to a Monday-evening time slot.

Chase joined the cast of CBS series S.W.A.T in 2019.