He was nominated for a 2002, Laurence Olivier Theatre Award for Best Performance in a Supporting Role in a Musical or Entertainment of 2001, for his performance in a West End production of My Fair Lady. Also in 2002, he appeared as Benedick in Gregory Doran’s production of Much Ado About Nothing with the Royal Shakespeare Company, opposite Harriet Walter. In 2002, he did an interview where he talked about playing Benedick in Much Ado About Nothing.

Since 2003, Le Prevost has been portraying Georges Simenon’s fictional detective Jules Maigret for BBC Radio, replacing the late Maurice Denham in the role. In 2005, he appeared as W. Somerset Maugham in a BBC Radio adaption of the author’s novel The Razor’s Edge.

His film work includes Clockwise, The Girl in a Swing, and Shakespeare in Love. In 2009 he appeared on television in Margaret.

In July 2010, he appeared in a double bill of Tom Stoppard’s The Real Inspector Hound and Richard Brinsley Sheridan’s The Critic at the Minerva Theatre, Chichester.

In 2010 he appeared in ITV drama Wild at Heart as Gene.

From February 2015, he appeared in Man and Superman at the National Theatre, London.

In 2015, he appeared as Count Fiskon in the BBC TV series Father Brown episode “The Lair of the Libertines”. In 2016, he had a cameo role as an investment banker for a fictitious firm London-based firm called Waterston and Price in the Danish thriller Follow the Money, which was shown on BBC 4 in spring of that year.