In 2015 she performed her first song on YouTube named “Medabrim”. Following its success, that year she released another song called “Killer. The provocative video clip for the song caused a stir due to Kirel’s young age. She released additional songs, which were featured on YouTube and played on various Israeli radio stations, including the songs – “Yesh Be Ahava”, which was the first song to enter the Galgalatz playlist, “Rak Ata”, “Hatzi Meshuga”, “Bye Lahofesh” and “Ten Li Siman”. At the end of 2016, she won the award “Singer of the Year” at the children’s elected ceremony. On February 26, 2017, Kirel began hosting the “Lipstar” musical program on kidZ channel, alongside Sagi Breitner. In May 2017, she released a song called “Makon Leshinuy” which she sang in a duet with Avior Melasa who even wrote and composed the song. Kirel released several other songs during the year which were all marketing singles: “Lirkod”, “Kimeat Meforsemet”, “Wow”, “Mi Yiten Li Et Ha’Koach”. On June 22, she starred in the teen movie “Nearly Famous”, alongside Omer Dror. In the same year, she also appeared in the theater production “The Three Musketeers” alongside Omer Dror. On August 28, Kirel released a single which she performed with Agam Bohbut, a cover version of Danny Sanderson’s song; “Etzel Ha’Doda ve Ha’Dod”, as part of a campaign for Bezeq. In November 2017, she represented Israel at the “MTV Europe Music Awards”, in the “International Artist” category.

On January 1, 2018, began starring in the television series “Kfula”, In the roles of Noa Kirel (herself) and Kitty Popper (Libby Omer); A blogger who writes anything that happens to her famous self. The series airs on the KidZ channel on yes and HOT. On February 18, she began participating in Israel’s Got Talent as a judge. On March 25, 2018, she released the single “Megibor Le’Oyev”. On May 1 of that year, the series “Shilton Ha’Tzlalim” has aired, where she plays the role of Basemet. On August 9, a theater production “Kfula show” starring Kirel and the stars of the Kfula series has opened in Menora Mivtachim Arena. On August 20, the theme song for the #Freestyle Festigel production was released. In early September 2018, a full-length movie came out to promote the show. The show itself runs from November 13, 2018, to January 8, 2019. On September 5, Kirl featured in the song “Cinderella”, of The Ultras. On September 20, Kirel collaborated with “Ma Kashur Trio” and Itai Levy, on a new cover version of Aric Sinai’s “Siba Tova” song, “Hine Ze Ba”, for a HOT campaign. In October, Kirel was selected for the second time to represent Israel at the MTV Europe Music Awards but was unable to attend the ceremony in Spain due to a tight schedule. That month, Kirel began to be the new cosmetic company “Keff” presenter. On November 2, she released the song “Zikaron Yashan” in collaboration with the singer Jonathan Mergui, as part of the Festigel. On November 11, the cast of the 2018 Festigel, including Kirel, released the original song “Tinshom” with a video clip. On November 23, she participated in a tribute show in memory of Amir Fryszer Guttman called “As if there is no tomorrow” alongside many artists. In December 2018, Kirel led a campaign with the KidZ Channel and the Israeli National Road Safety Authority for wearing a helmet while cycling. In May 2020 she participated in a Yes (Israel) commercial.

In 2020, she was enlisted to the Israel Defense Forces (IDF), and serves in a military band.

In June 2020, it was officially announced that Noa has signed a contract with the American label, Atlantic Records.